Spravato
Spravato® Treatment at Mend Psychiatry
A Breakthrough Option for Treatment-Resistant Depression
At Mend Psychiatry, we are committed to providing compassionate, evidence-based care for individuals struggling with depression that hasn’t responded to traditional treatments. Spravato® (esketamine) is an FDA-approved nasal spray designed to help adults with treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts or behaviors find relief when other options have failed.
What Is Spravato® and How Does It Work?
Spravato® works differently than standard antidepressants. While most medications target serotonin or norepinephrine, Spravato® acts on the NMDA receptor in the brain’s glutamate system, helping restore disrupted neural pathways and improve mood regulation. This unique mechanism often leads to faster symptom improvement—sometimes within days—rather than weeks.
Who Is Eligible for Spravato®?
You may be a candidate if:
- You are an adult diagnosed with treatment-resistant depression (failed at least two antidepressants at adequate doses and duration).
- You have major depressive disorder with suicidal thoughts or behaviors.
- You are medically cleared for treatment (blood pressure and cardiovascular health will be assessed).
Spravato® is always used in combination with an oral antidepressant and administered under medical supervision in a certified treatment center.
What to Expect During Treatment
- Administration: Spravato® is self-administered as a nasal spray under the guidance of a clinician.
- Observation: Each session lasts about two hours, including a monitoring period for safety.
- Frequency: Typically twice weekly for the first 4 weeks (induction phase), then weekly or bi-weekly for maintenance.
- Safety: You cannot drive until the next day, so arrange transportation. Our team will monitor your blood pressure and overall well-being throughout the session.
Common Questions
Many patients notice improvement within the first few treatments, with significant benefits often seen by week 4.
Yes—when administered in a REMS-certified clinic like Mend Psychiatry. We follow strict protocols to ensure your safety and comfort.
Most major insurers cover Spravato® with prior authorization. Our team will assist with the approval process.
Why Choose Mend Psychiatry?
We combine cutting-edge treatments with compassionate care. Our clinicians provide personalized treatment plans and ongoing support to help you achieve lasting relief.
Ready to Take the Next Step?
If you’ve tried multiple antidepressants without success, Spravato® may be the breakthrough you’ve been waiting for.
Schedule a consultation today to find out if Spravato® is right for you.
Reach Out Today!
It’s important not to attempt a self-diagnosis of any specific mental health conditions, but rather to take notice and be aware of triggers, thoughts, emotions, and behaviors that feel unhealthy or disrupt your everyday life. We are often hyper-aware of conditions related to flaws in our physical health, but mental health is equally important. Determining whether or not to see a psychiatrist often requires a candid self-assessment of your symptoms and day-to-day experiences. To even make this amount of individual progress is a significant step in the right direction toward achieving quality mental health. If you are experiencing the symptoms of mental health conditions it is essential to seek help and guidance in treating them.
